SMases D-IN-1, CAS [[849020-48-0]] Preis auf Anfrage
Artikelnummer:
MCE-HY-182413
Hersteller Artikelnummer:
HY-182413
Alternativnummer:
MCE-HY-182413-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
SMases D-IN-1 is an inhibitor of SMase D (sphingomyelinase D) from Loxosceles (brown recluse spider), with a Ki value of 0.54 µM. SMases D-IN-1 inhibits the hydrolysis of sphingomyelin substrates by recombinant and native SMases D, reduces the binding ability of SMases D to human red blood cells, and prevents the shedding of glycophorin C from the surface of human red blood cells. SMases D-IN-1 partially inhibits Loxosceles venom-induced death of human keratinocytes and also suppresses systemic reactions triggered by Loxosceles venom. SMases D-IN-1 can be used in studies related to recluse spider envenomation[1].
Molekulargewicht:
412.49
CAS Nummer:
[849020-48-0]
Formel:
C19H16N4O3S2
Target-Kategorie:
Phospholipase
Anwendungsbeschreibung:
MCE Product type: Reference compound
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