SMases D-IN-1, CAS [[849020-48-0]] Preis auf Anfrage

Product Overview

• Article Name: SMases D-IN-1, CAS [[849020-48-0]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-182413
• Supplier Catalog Number: HY-182413
• Alternative Catalog Number: MCE-HY-182413-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

SMases D-IN-1 is an inhibitor of SMase D (sphingomyelinase D) from Loxosceles (brown recluse spider), with a Ki value of 0.54 µM. SMases D-IN-1 inhibits the hydrolysis of sphingomyelin substrates by recombinant and native SMases D, reduces the binding ability of SMases D to human red blood cells, and prevents the shedding of glycophorin C from the surface of human red blood cells. SMases D-IN-1 partially inhibits Loxosceles venom-induced death of human keratinocytes and also suppresses systemic reactions triggered by Loxosceles venom. SMases D-IN-1 can be used in studies related to recluse spider envenomation[1].

Product Properties

• Molecular Weight: 412.49
• CAS Number: [849020-48-0]
• Formula: C19H16N4O3S2
• Target: Phospholipase

Application Notes

• Application Notes: MCE Product type: Reference compound