FJ9, CAS [[873841-43-1]]

Produktübersicht

• Artikelname: FJ9, CAS [[873841-43-1]]
• Artikelnummer: MCE-HY-182624
• Hersteller Artikelnummer: HY-182624
• Alternativnummer: MCE-HY-182624-10MG, MCE-HY-182624-100MG, MCE-HY-182624-50MG, MCE-HY-182624-1MG, MCE-HY-182624-5MG, MCE-HY-182624-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

FJ9 is a NHERF1/PDZ inhibitor with human NHERF1 PDZ1 IC50 1540 µM, NHERF1 PDZ2 IC50 160 µM, and Frizzled-7-Dishevelled PDZ complex Ki 10 µM. FJ9 binds ligand-binding pockets of NHERF1 PDZ domains to block cognate ligand interactions, disrupts Frizzled-7-Dishevelled interactions, and down-regulates canonical Wnt signaling. FJ9 induces apoptosis in cancer cells with intact beta-catenin signaling. FJ9 can be used for the research of non-small cell lung cancer, melanoma[1][2].

Produkteigenschaften

• Molekulargewicht: 365.47
• CAS Nummer: [873841-43-1]
• Formel: C23H27NO3
• Target-Kategorie: Apoptosis,Na+/H+ Exchanger (NHE),Wnt

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound