PSB-16671 is an allosteric agonist of GPR84. PSB-16671 recruits beta-arrestins and couples to Gi, enhances the Gi activation potency of orthosteric agonists, and exerts a synergistic effect with orthosteric agonists. PSB-16671 promotes G protein activation and partial chemotaxis independent of GPR84 in mouse neutrophils, maintains the phagocytic function of macrophages against cancer cells without inducing receptor desensitization. PSB-16671 can be used in cancer-related research[1][2][3].
Molekulargewicht:
318.27
CAS Nummer:
[2094630-35-8]
Formel:
C17H10F4N2
Target-Kategorie:
GPR84
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
