KRAS-IN-58 is a KRAS inhibitor with a IC50 of 0.223 µM against KRASG12D. KRAS-IN-58 binds to KRASG12C and KRASG12D proteins, and reduces the levels of phosphorylated Raf1, AKT and ERK in pancreatic cancer cells. KRAS-IN-58 can be used for the research of pancreatic cancer[1].
Molekulargewicht:
451.52
Formel:
C21H17N5O3S2
Target-Kategorie:
Akt,ERK,Raf,Ras
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
