Ferroptosis inducer-15, CAS [[3097756-33-4]] Preis auf Anfrage
Artikelnummer:
MCE-HY-182802
Hersteller Artikelnummer:
HY-182802
Alternativnummer:
MCE-HY-182802-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Ferroptosis inducer-15 is a ferroptosis inducer. Ferroptosis inducer-15 downregulates GPX4 expression, triggers lipid peroxidation via ROS accumulation, and disrupts mitochondrial membrane potential to drive ferroptosis. Ferroptosis inducer-15 increases splenic CD4+ T cell proportion, promotes CD8+ cytotoxic T cell tumor infiltration, and activates antitumor immune responses. Ferroptosis inducer-15 exerts antiproliferative activity against colorectal cancer cells and inhibits tumor growth in xenograft mice models without significant body weight loss. Ferroptosis inducer-15 can be used for the research of cancer, such as colorectal cancer[1].
Molekulargewicht:
666.62
CAS Nummer:
[3097756-33-4]
Formel:
C31H41NO10Se
Target-Kategorie:
Ferroptosis,Glutathione Peroxidase,Mitochondrial Metabolism,Reactive Oxygen Species (ROS)
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten