Ferroptosis inducer-15, CAS [[3097756-33-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-182802
Supplier Catalog Number:
HY-182802
Alternative Catalog Number:
MCE-HY-182802-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Ferroptosis inducer-15 is a ferroptosis inducer. Ferroptosis inducer-15 downregulates GPX4 expression, triggers lipid peroxidation via ROS accumulation, and disrupts mitochondrial membrane potential to drive ferroptosis. Ferroptosis inducer-15 increases splenic CD4+ T cell proportion, promotes CD8+ cytotoxic T cell tumor infiltration, and activates antitumor immune responses. Ferroptosis inducer-15 exerts antiproliferative activity against colorectal cancer cells and inhibits tumor growth in xenograft mice models without significant body weight loss. Ferroptosis inducer-15 can be used for the research of cancer, such as colorectal cancer[1].
Molecular Weight:
666.62
CAS Number:
[3097756-33-4]
Formula:
C31H41NO10Se
Target:
Ferroptosis,Glutathione Peroxidase,Mitochondrial Metabolism,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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