EZM8266, CAS [[2140164-84-5]]

Produktübersicht

• Artikelname: EZM8266, CAS [[2140164-84-5]]
• Artikelnummer: MCE-HY-183058
• Hersteller Artikelnummer: HY-183058
• Alternativnummer: MCE-HY-183058-100MG, MCE-HY-183058-5MG, MCE-HY-183058-10MG, MCE-HY-183058-25MG, MCE-HY-183058-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

EZM8266 is an orally active and selective G9a (EHMT2) histone methyltransferase inhibitor with a human EHMT2 IC50 of 1 pM. EZM8266 reduces repressive H3K9me2 marks at immune-stimulatory gene and endogenous retroviral element promoters. EZM8266 reduces colony formation, migration, and invasion of cancer cells. EZM8266 enhances IFN-gamma response, increases MHC class I expression, and enhances CXCL10-mediated T cell recruitment in cancer cells. EZM8266 can be used for the research of hepatocellular carcinoma[1][2].

Produkteigenschaften

• Molekulargewicht: 373.45
• CAS Nummer: [2140164-84-5]
• Formel: C19H27N5O3
• Target-Kategorie: Histone Methyltransferase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound