Androgen receptor antagonist-14 (Compound S-94) is a selective antagonist of the T878A mutant androgen receptor (AR) with an IC50 of 0.38 µM. Androgen receptor antagonist-14 selectively antagonizes the transcriptional activity of the ART878A, ARF877L/T878A and ARH875Y/T878A mutant androgen receptors. Androgen receptor antagonist-14 exhibits anticancer activity against prostate cancer. Androgen receptor antagonist-14 can be used in the research of prostate cancer[1].
Molekulargewicht:
427.50
Formel:
C26H25N3O3
Target-Kategorie:
Androgen Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
