RIPK1/RIPK3-PPI-IN-1, CAS [[2915280-95-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: RIPK1/RIPK3-PPI-IN-1, CAS [[2915280-95-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-183564
• Hersteller Artikelnummer: HY-183564
• Alternativnummer: MCE-HY-183564-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

RIPK1/RIPK3-PPI-IN-1 is an orally active dual-target inhibitor of RIPK1/RIPK3, with a Kd value of 2.4 nM for RIPK1 and 24 nM for RIPK3. RIPK1/RIPK3-PPI-IN-1 inhibits the phosphorylation of RIPK1, RIPK3 and MLKL, thereby suppressing necroptosis. RIPK1/RIPK3-PPI-IN-1 restores body temperature, improves survival rate, and reduces IL-1beta/IL-6 levels in serum and multiple organs of Mus musculus, thus alleviating TNF-alpha-induced systemic inflammatory response syndrome. RIPK1/RIPK3-PPI-IN-1 can be used in research related to systemic inflammatory response syndrome[1].

Produkteigenschaften

• Molekulargewicht: 546.55
• CAS Nummer: [2915280-95-2]
• Formel: C27H20F2N6O3S
• Target-Kategorie: Interleukin Related,Necroptosis,RIP kinase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound