RIPK1/RIPK3-PPI-IN-1, CAS [[2915280-95-2]] Preis auf Anfrage

Product Overview

• Article Name: RIPK1/RIPK3-PPI-IN-1, CAS [[2915280-95-2]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-183564
• Supplier Catalog Number: HY-183564
• Alternative Catalog Number: MCE-HY-183564-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

RIPK1/RIPK3-PPI-IN-1 is an orally active dual-target inhibitor of RIPK1/RIPK3, with a Kd value of 2.4 nM for RIPK1 and 24 nM for RIPK3. RIPK1/RIPK3-PPI-IN-1 inhibits the phosphorylation of RIPK1, RIPK3 and MLKL, thereby suppressing necroptosis. RIPK1/RIPK3-PPI-IN-1 restores body temperature, improves survival rate, and reduces IL-1beta/IL-6 levels in serum and multiple organs of Mus musculus, thus alleviating TNF-alpha-induced systemic inflammatory response syndrome. RIPK1/RIPK3-PPI-IN-1 can be used in research related to systemic inflammatory response syndrome[1].

Product Properties

• Molecular Weight: 546.55
• CAS Number: [2915280-95-2]
• Formula: C27H20F2N6O3S
• Target: Interleukin Related,Necroptosis,RIP kinase

Application Notes

• Application Notes: MCE Product type: Reference compound