SHIP1-IN-1, CAS [[3027375-00-1]] Preis auf Anfrage

Produktübersicht

• Artikelname: SHIP1-IN-1, CAS [[3027375-00-1]] Preis auf Anfrage
• Artikelnummer: MCE-HY-183593
• Hersteller Artikelnummer: HY-183593
• Alternativnummer: MCE-HY-183593-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

SHIP1-IN-1 is an orally active, blood-brain barrier-permeable SHIP1 ligand. SHIP1-IN-1 exhibits IC50 values of 384 µM and 177 µM against human SHIP1, and an IC50 value of 379 µM against murine SHIP1. SHIP1-IN-1 alters the binding state of SHIP1 to phosphatidylinositol membranes, and regulates phosphoinositide pools and phosphorylated AKT levels. SHIP1-IN-1 enhances the uptake of myelin/membrane fragments and amyloid proteins by microglia, alters gene expression and reduces IL-1beta levels. SHIP1-IN-1 can be used in studies related to Alzheimers disease[1][2].

Produkteigenschaften

• Molekulargewicht: 368.86
• CAS Nummer: [3027375-00-1]
• Formel: C20H21ClN4O
• Target-Kategorie: Akt,Interleukin Related,Phosphatase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound