AZD4956, CAS [[3045469-78-8]]

Produktübersicht

• Artikelname: AZD4956, CAS [[3045469-78-8]]
• Artikelnummer: MCE-HY-183630
• Hersteller Artikelnummer: HY-183630
• Alternativnummer: MCE-HY-183630-1MG, MCE-HY-183630-5MG, MCE-HY-183630-10MG, MCE-HY-183630-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

AZD4956 is a potent and selective DNA polymerase theta (POLQ) inhibitor. AZD4956 exhibits an IC50 value of less than 3 µmol/L against POLQ and 3.4 µmol/L against MMEJ. AZD4956 suppresses the MMEJ pathway and enhances the activity of DNA-damaging agents in HRR-deficient cellular contexts. AZD4956 shows antitumor activity in BRCA1/2-mutated triple-negative breast cancer and prostate cancer models. AZD4956 can be used for the study of homologous recombination-deficient tumors[1].

Produkteigenschaften

• Molekulargewicht: 566.44
• CAS Nummer: [3045469-78-8]
• Formel: C28H25Cl2N5O4
• Target-Kategorie: DNA/RNA Synthesis

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound