AZD4956, CAS [[3045469-78-8]]

Product Overview

• Article Name: AZD4956, CAS [[3045469-78-8]]
• Biozol Catalog Number: MCE-HY-183630
• Supplier Catalog Number: HY-183630
• Alternative Catalog Number: MCE-HY-183630-1MG, MCE-HY-183630-5MG, MCE-HY-183630-10MG, MCE-HY-183630-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

AZD4956 is a potent and selective DNA polymerase theta (POLQ) inhibitor. AZD4956 exhibits an IC50 value of less than 3 µmol/L against POLQ and 3.4 µmol/L against MMEJ. AZD4956 suppresses the MMEJ pathway and enhances the activity of DNA-damaging agents in HRR-deficient cellular contexts. AZD4956 shows antitumor activity in BRCA1/2-mutated triple-negative breast cancer and prostate cancer models. AZD4956 can be used for the study of homologous recombination-deficient tumors[1].

Product Properties

• Molecular Weight: 566.44
• CAS Number: [3045469-78-8]
• Formula: C28H25Cl2N5O4
• Target: DNA/RNA Synthesis

Application Notes

• Application Notes: MCE Product type: Reference compound