KT109, CAS [[1402612-55-8]]

Produktübersicht

• Artikelname: KT109, CAS [[1402612-55-8]]
• Artikelnummer: MCE-HY-18540
• Hersteller Artikelnummer: HY-18540
• Alternativnummer: MCE-HY-18540-10MMX1ML,MCE-HY-18540-100MG,MCE-HY-18540-50MG,MCE-HY-18540-25MG,MCE-HY-18540-10MG,MCE-HY-18540-5MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

KT109 is a potent and an isoform-selective inhibitor of diacylglycerol lipase-beta (DAGLbeta) with an IC50 of 42 nM. KT109 has ~60-fold selectivity for DAGLbeta over DAGLalpha. KT109 shows inhibitory activity against PLA2G7 (IC50=1 µM). KT109 shows negligible activity against FAAH, MGLL, ABHD11, and cytosolic phospholipase A2 (cPLA2 or PLA2G4A). KT109 perturbs a lipid network involved in macrophage inflammatory responses and lowers 2-Arachidonoylglycerol (HY-W011051), Arachidonic acid (HY-109590) and eicosanoids in mouse peritoneal macrophages[1].

Produkteigenschaften

• Molekulargewicht: 422.52
• Reinheit: 99.86
• CAS Nummer: [1402612-55-8]
• Formel: C27H26N4O
• Target-Kategorie: DAGL,MAGL

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound