Lifirafenib (hydrochloride), CAS [[2025320-97-0]] Preis auf Anfrage
Artikelnummer:
MCE-HY-18957C
Hersteller Artikelnummer:
HY-18957C
Alternativnummer:
MCE-HY-18957C-1UNIT
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
BGB-283 (hydrochloride)
Lifirafenib hydrochloride (BGB-283 hydrochloride) is a novel, reversible B-RAFV600E inhibitor with antitumor activity. Lifirafenib has shown potent antitumor activity against solid tumors with B-RAFV600E mutations, such as melanoma, thyroid cancer, and low-grade serous ovarian cancer. Lifirafenib exhibits selective cytotoxicity in vitro, preferentially inhibiting the proliferation of cancer cells with B-RAFV600E and EGFR mutations/amplification. Lifirafenib can achieve dose-dependent inhibition of tumor growth in animal models, accompanied by partial and complete tumor shrinkage[1].
Molekulargewicht:
514.88
CAS Nummer:
[2025320-97-0]
Formel:
C25H18ClF3N4O3
Target-Kategorie:
Endogenous Metabolite
Anwendungsbeschreibung:
MCE Product type: Reference compound
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
