Lifirafenib (hydrochloride), CAS [[2025320-97-0]] Preis auf Anfrage

Product Overview

• Article Name: Lifirafenib (hydrochloride), CAS [[2025320-97-0]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-18957C
• Supplier Catalog Number: HY-18957C
• Alternative Catalog Number: MCE-HY-18957C-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: BGB-283 (hydrochloride)

Product Description

Lifirafenib hydrochloride (BGB-283 hydrochloride) is a novel, reversible B-RAFV600E inhibitor with antitumor activity. Lifirafenib has shown potent antitumor activity against solid tumors with B-RAFV600E mutations, such as melanoma, thyroid cancer, and low-grade serous ovarian cancer. Lifirafenib exhibits selective cytotoxicity in vitro, preferentially inhibiting the proliferation of cancer cells with B-RAFV600E and EGFR mutations/amplification. Lifirafenib can achieve dose-dependent inhibition of tumor growth in animal models, accompanied by partial and complete tumor shrinkage[1].

Product Properties

• Molecular Weight: 514.88
• CAS Number: [2025320-97-0]
• Formula: C25H18ClF3N4O3
• Target: Endogenous Metabolite

Application Notes

• Application Notes: MCE Product type: Reference compound