(rac)-ZK-304709, CAS [[1010440-84-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: (rac)-ZK-304709, CAS [[1010440-84-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-19471
• Hersteller Artikelnummer: HY-19471
• Alternativnummer: MCE-HY-19471-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

(rac)-ZK-304709 is an isoform of ZK-304709 and is an orally active multi-targeted tumor growth inhibitor that inhibits multiple cell cycle-dependent kinases (CDKs), vascular endothelial growth factor receptor kinases (VEGF-RTKs), and platelet-derived growth factor receptor kinase beta (PDGF-RTKbeta). (rac)-ZK-304709 can dose-dependently inhibit the proliferation and colony formation of neuroendocrine tumor (NET) cells. (rac)-ZK-304709 directly acts on NET cells by inducing G2 cell cycle arrest and apoptosis, while reducing the expression of MCL1, survivin, and HIF1alpha. (rac)-ZK-304709 effectively controls tumor growth by inducing apoptosis and inhibiting tumor-induced angiogenesis, and may become a potential agent for inhibiting NET[1].

Produkteigenschaften

• Molekulargewicht: 444.96
• CAS Nummer: [1010440-84-2]
• Formel: C22H29ClN6O2
• Target-Kategorie: Apoptosis,CDK,Drug Isomer,Survivin,VEGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound