THS-044, CAS [[62054-67-5]]

Produktübersicht

• Artikelname: THS-044, CAS [[62054-67-5]]
• Artikelnummer: MCE-HY-19621
• Hersteller Artikelnummer: HY-19621
• Alternativnummer: MCE-HY-19621-10MMX1ML,MCE-HY-19621-10MG,MCE-HY-19621-100MG,MCE-HY-19621-5MG,MCE-HY-19621-50MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

THS-044 is a modulator of the formation of the HIF2alpha/ARNT heterodimer. THS-044 binding stabilizes the HIF2alpha PAS-B folded state (KD = 2 µM), for regulating HIF2 activity in endogenous and pathological settings, and does not bind to HIF1alpha or ARNT PAS-B. THS-044 increases the KD of the heterodimer formed by HIF2alpha PAS-B and ARNT PAS-B from 120 µM to 400 µM. THS-044 can be used for the study of diseases related to hypoxia[1][2].

Produkteigenschaften

• Molekulargewicht: 291.23
• Reinheit: 99.67
• CAS Nummer: [62054-67-5]
• Formel: C11H12F3N3O3
• Target-Kategorie: HIF/HIF Prolyl-Hydroxylase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound