GSK 3008348, CAS [[1629249-33-7]]

Artikelnummer: MCE-HY-19767
Artikelname: GSK 3008348, CAS [[1629249-33-7]]
Artikelnummer: MCE-HY-19767
Hersteller Artikelnummer: HY-19767
Alternativnummer: MCE-HY-19767-25MG,MCE-HY-19767-1G,MCE-HY-19767-50MG,MCE-HY-19767-5MG,MCE-HY-19767-100MG,MCE-HY-19767-10MG
Hersteller: MedchemExpress
Kategorie: Biochemikalien
GSK 3008348 is a small molecule antagonist of integrin alphavbeta6 with IC50 values for alphavbeta6, alphavbeta1, alphavbeta3, alphavbeta5, and alphavbeta8 are 1.50, 2.83, 12.53, 4.00, and 2.26 nM, respectively. GSK 3008348 can target the alphavbeta6 integrin, inhibit TGF-beta activation, and thereby alleviate the fibrotic process. GSK 3008348 prevents the binding of the foot-and-mouth disease virus (FMDV) to the alphavbeta6 integrin receptor on the surface of host cells, thereby inhibiting the entry of the virus. GSK 3008348 can be used for research on pulmonary fibrosis and various types of cancer[1][2][3][4].
Molekulargewicht: 487.64
Reinheit: 98.04
CAS Nummer: [1629249-33-7]
Formel: C29H37N5O2
Target-Kategorie: Integrin,TGF-beta Receptor
Anwendungsbeschreibung: Reference compound