GSK 3008348, CAS [[1629249-33-7]]

Product Overview

• Article Name: GSK 3008348, CAS [[1629249-33-7]]
• Biozol Catalog Number: MCE-HY-19767
• Supplier Catalog Number: HY-19767
• Alternative Catalog Number: MCE-HY-19767-25MG,MCE-HY-19767-1G,MCE-HY-19767-50MG,MCE-HY-19767-5MG,MCE-HY-19767-100MG,MCE-HY-19767-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

GSK 3008348 is a small molecule antagonist of integrin alphavbeta6 with IC50 values for alphavbeta6, alphavbeta1, alphavbeta3, alphavbeta5, and alphavbeta8 are 1.50, 2.83, 12.53, 4.00, and 2.26 nM, respectively. GSK 3008348 can target the alphavbeta6 integrin, inhibit TGF-beta activation, and thereby alleviate the fibrotic process. GSK 3008348 prevents the binding of the foot-and-mouth disease virus (FMDV) to the alphavbeta6 integrin receptor on the surface of host cells, thereby inhibiting the entry of the virus. GSK 3008348 can be used for research on pulmonary fibrosis and various types of cancer[1][2][3][4].

Product Properties

• Molecular Weight: 487.64
• Purity: 98.04
• CAS Number: [1629249-33-7]
• Formula: C29H37N5O2
• Target: Integrin,TGF-beta Receptor

Application Notes

• Application Notes: Reference compound