LY2775240 is an orally available phosphodiesterase 4 (PDE4) inhibitor with potent inhibitory activity against PDE4A (IC50 = 0.09 nM), PDE4B (IC50 = 0.09 nM), and PDE4D (IC50 = 0.14 nM), and exhibits an IC50 of 2.4 nM against PDE4C. LY2775240 is a highly selective agent that reduces TNFalpha production during immune activation. It effectively lowers TNFalpha levels in rodent and cynomolgus monkey models. LY2775240 can be used in research on psoriasis[1].
Molekulargewicht:
485.58
CAS Nummer:
[1628160-15-5]
Formel:
C26H35N3O6
Target-Kategorie:
Phosphodiesterase (PDE),TNF Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound1
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
