Tyrphostin AG 879 (AG 879) is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation (IC50 of 10 µM), but not TrKB and TrKC. Tyrphostin AG 879 is also a selective ErbB2 tyrosine kinase inhibitor with an IC50 of 1 µM, and has at least 500-fold higher selectivity to ErbB2 than EGFR. Tyrphostin AG 879 has anticancer activity[1][2][3].
Molekulargewicht:
316.46
Reinheit:
99.26
CAS Nummer:
[148741-30-4]
Formel:
C18H24N2OS
Target-Kategorie:
Apoptosis,EGFR,Trk Receptor
Anwendungsbeschreibung:
MCE Product type: Reference compound1
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