Tyrphostin AG 879 (AG 879) is a tyrosine kinase inhibitor that inhibits TrKA phosphorylation (IC50 of 10 µM), but not TrKB and TrKC. Tyrphostin AG 879 is also a selective ErbB2 tyrosine kinase inhibitor with an IC50 of 1 µM, and has at least 500-fold higher selectivity to ErbB2 than EGFR. Tyrphostin AG 879 has anticancer activity[1][2][3].
Molecular Weight:
316.46
Purity:
99.26
CAS Number:
[148741-30-4]
Formula:
C18H24N2OS
Target:
Apoptosis,EGFR,Trk Receptor
Application Notes:
MCE Product type: Reference compound
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