Synucleozid-2.0 is a small-molecule inhibitor targeting the iron-responsive element (IRE) structure in the 5 untranslated region (5UTR) of SNCA mRNA. Synucleozid-2.0 inhibits ribosome assembly onto SNCA mRNA and selectively reduces alpha-synuclein protein translation. Synucleozid-2.0 is promising for research of Parkinsons disease (PD) and related alpha-synucleinopathies[1].
Molekulargewicht:
506.38
CAS Nummer:
[613226-91-8]
Formel:
C22H16BrN7OS
Target-Kategorie:
DNA/RNA Synthesis,alpha-synuclein
Anwendungsbeschreibung:
MCE Product type: Reference compound
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