Synucleozid-2.0, CAS [[613226-91-8]]

Produktübersicht

• Artikelname: Synucleozid-2.0, CAS [[613226-91-8]]
• Artikelnummer: MCE-HY-401209
• Hersteller Artikelnummer: HY-401209
• Alternativnummer: MCE-HY-401209-10MG,MCE-HY-401209-5MG,MCE-HY-401209-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Synucleozid-2.0 is a blood-brain barrier-permeable inhibitor that binds to the IRE of SNCA mRNA, with a EC50 of 2.9 µM and a Kd value of 1.8 µM. Synucleozid-2.0 selectively binds to and stabilizes the A bulge and adjacent closed base pairs in the 5 UTR IRE of SNCA mRNA, blocks the translation process and reduces intracellular levels of alpha-synuclein. Synucleozid-2.0 exerts cytoprotective effects against cytotoxicity induced by alpha-synuclein preformed fibrils. Synucleozid-2.0 is applicable to the research of Parkinsons disease[1].

Produkteigenschaften

• Molekulargewicht: 506.38
• CAS Nummer: [613226-91-8]
• Formel: C22H16BrN7OS
• Target-Kategorie: DNA/RNA Synthesis,alpha-synuclein

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound