Synucleozid-2.0, CAS [[613226-91-8]]

Product Overview

• Article Name: Synucleozid-2.0, CAS [[613226-91-8]]
• Biozol Catalog Number: MCE-HY-401209
• Supplier Catalog Number: HY-401209
• Alternative Catalog Number: MCE-HY-401209-10MG,MCE-HY-401209-5MG,MCE-HY-401209-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Synucleozid-2.0 is a blood-brain barrier-permeable inhibitor that binds to the IRE of SNCA mRNA, with a EC50 of 2.9 µM and a Kd value of 1.8 µM. Synucleozid-2.0 selectively binds to and stabilizes the A bulge and adjacent closed base pairs in the 5 UTR IRE of SNCA mRNA, blocks the translation process and reduces intracellular levels of alpha-synuclein. Synucleozid-2.0 exerts cytoprotective effects against cytotoxicity induced by alpha-synuclein preformed fibrils. Synucleozid-2.0 is applicable to the research of Parkinsons disease[1].

Product Properties

• Molecular Weight: 506.38
• CAS Number: [613226-91-8]
• Formula: C22H16BrN7OS
• Target: DNA/RNA Synthesis,alpha-synuclein

Application Notes

• Application Notes: MCE Product type: Reference compound