Desmethyl-QCA276, CAS [[2126819-55-2]] Preis auf Anfrage

Produktübersicht

• Artikelname: Desmethyl-QCA276, CAS [[2126819-55-2]] Preis auf Anfrage
• Artikelnummer: MCE-HY-44103
• Hersteller Artikelnummer: HY-44103
• Alternativnummer: MCE-HY-44103-1UNIT
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: PROTAC BRD4-binding moiety 4

Produktbeschreibung

Desmethyl-QCA276 (PROTAC BRD4-binding moiety 4), the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM[1]. Desmethyl-QCA276 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Produkteigenschaften

• Molekulargewicht: 387.46
• CAS Nummer: [2126819-55-2]
• Formel: C21H17N5OS
• Target-Kategorie: Ligands for Target Protein for PROTAC

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound