Desmethyl-QCA276, CAS [[2126819-55-2]] Preis auf Anfrage

Product Overview

• Article Name: Desmethyl-QCA276, CAS [[2126819-55-2]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-44103
• Supplier Catalog Number: HY-44103
• Alternative Catalog Number: MCE-HY-44103-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: PROTAC BRD4-binding moiety 4

Product Description

Desmethyl-QCA276 (PROTAC BRD4-binding moiety 4), the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM[1]. Desmethyl-QCA276 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Properties

• Molecular Weight: 387.46
• CAS Number: [2126819-55-2]
• Formula: C21H17N5OS
• Target: Ligands for Target Protein for PROTAC

Application Notes

• Application Notes: MCE Product type: Reference compound