Avagacestat, CAS [[1146699-66-2]]

Produktübersicht

• Artikelname: Avagacestat, CAS [[1146699-66-2]]
• Artikelnummer: MCE-HY-50845
• Hersteller Artikelnummer: HY-50845
• Alternativnummer: MCE-HY-50845-50MG,MCE-HY-50845-25MG,MCE-HY-50845-10MMX1ML,MCE-HY-50845-100MG,MCE-HY-50845-10MG,MCE-HY-50845-5MG,MCE-HY-50845-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: BMS-708163

Produktbeschreibung

Avagacestat (BMS-708163) is a potent inhibitor of gamma-secretase, with IC50s of 0.27 nM and 0.30 nM for Abeta42 and Abeta40 inhibition, Avagacestat (BMS-708163) also inhibits NICD (Notch IntraCellular Domain) with IC50 of 0.84 nM and shows weak inhibition of CYP2C19, with IC50 of 20 µM. Avagacestat can be used for Alzheimer disease research.

Produkteigenschaften

• Molekulargewicht: 520.89
• Reinheit: 99.92
• CAS Nummer: [1146699-66-2]
• Formel: C20H17ClF4N4O4S
• Target-Kategorie: Notch,gamma-secretase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1