SCH772984 is a highly selective and ATP-competitive ERK inhibitor, with IC50s of 4 and 1 nM for ERK1 and ERK2, respectively. SCH772984 has antitumor activity in MAPK inhibitor-na ve and MAPK inhibitor-resistant cells containing BRAF or RAS mutations[1].
Molekulargewicht:
587.67
Reinheit:
99.83
CAS Nummer:
[942183-80-4]
Formel:
C33H33N9O2
Target-Kategorie:
ERK
Anwendungsbeschreibung:
MCE Product type: Reference compound
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