Crizotinib, CAS [[877399-52-5]]

Produktübersicht

• Artikelname: Crizotinib, CAS [[877399-52-5]]
• Artikelnummer: MCE-HY-50878
• Hersteller Artikelnummer: HY-50878
• Alternativnummer: MCE-HY-50878-10MG,MCE-HY-50878-50MG,MCE-HY-50878-5MG,MCE-HY-50878-200MG,MCE-HY-50878-100MG,MCE-HY-50878-10MMX1ML,MCE-HY-50878-500MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: PF-02341066

Produktbeschreibung

Crizotinib (PF-02341066) is an orally bioavailable, ATP-competitive ALK and c-Met inhibitor with IC50s of 20 and 8 nM, respectively. Crizotinib inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays, respectively. Crizotinib is also a ROS1 inhibitor. Crizotinib has effective tumor growth inhibition[1][2][3].

Produkteigenschaften

• Molekulargewicht: 450.34
• Reinheit: 99.97
• CAS Nummer: [877399-52-5]
• Formel: C21H22Cl2FN5O
• Target-Kategorie: Anaplastic lymphoma kinase (ALK),c-Met/HGFR,Ligands for Target Protein for PROTAC,ROS Kinase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound1