Crizotinib-d5, CAS [[1395950-84-1]]

Produktübersicht

• Artikelname: Crizotinib-d5, CAS [[1395950-84-1]]
• Artikelnummer: MCE-HY-50878S
• Hersteller Artikelnummer: HY-50878S
• Alternativnummer: MCE-HY-50878S-1MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: PF-02341066-d5

Produktbeschreibung

Crizotinib-d5 is the deuterium labeled Crizotinib. Crizotinib (PF-02341066) is an orally bioavailable, ATP-competitive ALK and c-Met inhibitor with IC50s of 20 and 8 nM, respectively. Crizotinib inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays, respectively. Crizotinib is also a ROS1 inhibitor. Crizotinib has effective tumor growth inhibition[1][2][3].

Produkteigenschaften

• Molekulargewicht: 455.37
• Reinheit: 99.7
• CAS Nummer: [1395950-84-1]
• Formel: C21H17D5Cl2FN5O
• Target-Kategorie: Anaplastic lymphoma kinase (ALK),Autophagy,c-Met/HGFR,ROS Kinase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Isotope-Labeled Compounds