Crizotinib-d5, CAS [[1395950-84-1]] Preis auf Anfrage
Artikelnummer:
MCE-HY-50878S
Hersteller Artikelnummer:
HY-50878S
Alternativnummer:
MCE-HY-50878S-1MG
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
PF-02341066-d5
Crizotinib-d5 is the deuterium labeled Crizotinib. Crizotinib (PF-02341066) is an orally bioavailable, ATP-competitive ALK and c-Met inhibitor with IC50s of 20 and 8 nM, respectively. Crizotinib inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays, respectively. Crizotinib is also a ROS1 inhibitor. Crizotinib has effective tumor growth inhibition[1][2][3].
