ABT-737, CAS [[852808-04-9]]

Produktübersicht

• Artikelname: ABT-737, CAS [[852808-04-9]]
• Artikelnummer: MCE-HY-50907
• Hersteller Artikelnummer: HY-50907
• Alternativnummer: MCE-HY-50907-5MG,MCE-HY-50907-25MG,MCE-HY-50907-200MG,MCE-HY-50907-10MG,MCE-HY-50907-50MG,MCE-HY-50907-100MG,MCE-HY-50907-10MMX1ML
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

ABT-737, a BH3 mimetic, is a potent Bcl-2, Bcl-xL and Bcl-w inhibitor with EC50s of 30.3 nM, 78.7 nM, and 197.8 nM, respectively. ABT-737 induces the disruption of the BCL-2/BAX complex and BAK-dependent but BIM-independent activation of the intrinsic apoptotic pathway. ABT-737 induces autophagy and has the potential for acute myeloid leukemia (AML) research[1][2][3].

Produkteigenschaften

• Molekulargewicht: 813.43
• Reinheit: 99.64
• CAS Nummer: [852808-04-9]
• Formel: C42H45ClN6O5S2
• Target-Kategorie: Apoptosis,Autophagy,Bcl-2 Family,Mitophagy

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound