A-582941 dihydrochloride is a potent, selective and brain-penetrant partial agonist of alpha7 nAChR, with Kis of 10.8 and 16.7 nM in rat brain membranes and human frontal cortex, respectively. A-582941 dihydrochloride also binds to human 5-HT3 receptor with a Ki of 150 nM. A-582941 has the potential for cognitive deficits associated with various neurodegenerative and psychiatric disorders research[1][2].
Molekulargewicht:
353.29
Reinheit:
99.78
CAS Nummer:
[848591-90-2]
Formel:
C17H22Cl2N4
Target-Kategorie:
5-HT Receptor,nAChR
Anwendungsbeschreibung:
MCE Product type: Reference compound
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