Pevonedistat, CAS [[905579-51-3]]

Produktübersicht

• Artikelname: Pevonedistat, CAS [[905579-51-3]]
• Artikelnummer: MCE-HY-70062
• Hersteller Artikelnummer: HY-70062
• Alternativnummer: MCE-HY-70062-500MG,MCE-HY-70062-10MG,MCE-HY-70062-200MG,MCE-HY-70062-10MMX1ML,MCE-HY-70062-100MG,MCE-HY-70062-50MG,MCE-HY-70062-5MG,MCE-HY-70062-1MG,MCE-HY-70062-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: MLN4924

Produktbeschreibung

Pevonedistat (MLN4924) is a potent and selective NEDD8-activating enzyme (NAE) inhibitor with an IC50 of 4.7 nM. Pevonedistat induces the deregulation of S-phase DNA synthesis, thereby disrupting protein turnover mediated by cullin-RING ligase, leading to apoptosis of human tumor cells. Pevonedistat suppresses the growth of human tumour xenografts in mice[1].

Produkteigenschaften

• Molekulargewicht: 443.52
• Reinheit: 99.98
• CAS Nummer: [905579-51-3]
• Formel: C21H25N5O4S
• Target-Kategorie: Apoptosis,NEDD8-activating Enzyme

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound