BAY 61-3606 (hydrochloride), CAS [[1615197-10-8]]

Produktübersicht

• Artikelname: BAY 61-3606 (hydrochloride), CAS [[1615197-10-8]]
• Artikelnummer: MCE-HY-76474A
• Hersteller Artikelnummer: HY-76474A
• Alternativnummer: MCE-HY-76474A-5MG,MCE-HY-76474A-25MG,MCE-HY-76474A-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

BAY 61-3606 hydrochloride is an orally available, ATP-competitive, reversible and highly selective Syk inhibitor with a Ki of 7.5 nM and an IC50 of 10 nM . BAY 61-3606 hydrochloride reduces ERK1/2 and Akt phosphorylation in neuroblastoma cell. BAY 61-3606 hydrochloride induces a large decrease of Syk phosphorylation in K-rn cell lysates. BAY 61-3606 hydrochloride sensitizes TRAIL-induced apoptosis by downregulating Mcl-1 in breast cancer cells.

Produkteigenschaften

• Molekulargewicht: 426.86
• Reinheit: 98.08
• CAS Nummer: [1615197-10-8]
• Formel: C20H19ClN6O3
• Target-Kategorie: Apoptosis,Syk

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Reference compound