BAY 61-3606 (hydrochloride), CAS [[1615197-10-8]]

Product Overview

• Article Name: BAY 61-3606 (hydrochloride), CAS [[1615197-10-8]]
• Biozol Catalog Number: MCE-HY-76474A
• Supplier Catalog Number: HY-76474A
• Alternative Catalog Number: MCE-HY-76474A-5MG,MCE-HY-76474A-25MG,MCE-HY-76474A-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

BAY 61-3606 hydrochloride is an orally available, ATP-competitive, reversible and highly selective Syk inhibitor with a Ki of 7.5 nM and an IC50 of 10 nM . BAY 61-3606 hydrochloride reduces ERK1/2 and Akt phosphorylation in neuroblastoma cell. BAY 61-3606 hydrochloride induces a large decrease of Syk phosphorylation in K-rn cell lysates. BAY 61-3606 hydrochloride sensitizes TRAIL-induced apoptosis by downregulating Mcl-1 in breast cancer cells.

Product Properties

• Molecular Weight: 426.86
• Purity: 98.08
• CAS Number: [1615197-10-8]
• Formula: C20H19ClN6O3
• Target: Apoptosis,Syk

Application Notes

• Application Notes: Reference compound