Moexiprilat, CAS [[103775-14-0]] Preis auf Anfrage
Artikelnummer:
MCE-HY-A0114
Hersteller Artikelnummer:
HY-A0114
Alternativnummer:
MCE-HY-A0114-1MG,MCE-HY-A0114-5MG
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Alternative Synonym:
RS 10029
Moexiprilat is an inhibitor of angiotensin-converting enzyme (ACE, IC50=2.1 nM) and an active metabolite of the prodrug Moexipril (HY-117281). It is formed from moexipril in vivo by side chain ester hydrolysis. Moexiprilat (10 nM) prevents the estrone- or angiotensin II-stimulated proliferation of primary neonatal rat cardiac fibroblasts. It reduces mean arterial blood pressure and increases the levels of atrial natriuretic peptide, a marker of hypertension, in ovariectomized mice when administered at a dose of 50 mg/kg per day.
Molekulargewicht:
470.51
CAS Nummer:
[103775-14-0]
Formel:
C25H30N2O7
Target-Kategorie:
Angiotensin-converting Enzyme (ACE)
Anwendungsbeschreibung:
MCE Product type: Reference compound
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