Moexiprilat, CAS [[103775-14-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-A0114
Supplier Catalog Number:
HY-A0114
Alternative Catalog Number:
MCE-HY-A0114-1MG,MCE-HY-A0114-5MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Alternative Names:
RS 10029
Moexiprilat is an inhibitor of angiotensin-converting enzyme (ACE, IC50=2.1 nM) and an active metabolite of the prodrug Moexipril (HY-117281). It is formed from moexipril in vivo by side chain ester hydrolysis. Moexiprilat (10 nM) prevents the estrone- or angiotensin II-stimulated proliferation of primary neonatal rat cardiac fibroblasts. It reduces mean arterial blood pressure and increases the levels of atrial natriuretic peptide, a marker of hypertension, in ovariectomized mice when administered at a dose of 50 mg/kg per day.
Molecular Weight:
470.51
CAS Number:
[103775-14-0]
Formula:
C25H30N2O7
Target:
Angiotensin-converting Enzyme (ACE)
Application Notes:
MCE Product type: Reference compound
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