Triflusal-d3, CAS [[2748541-63-9]] Preis auf Anfrage
Artikelnummer:
MCE-HY-B0531S
Hersteller Artikelnummer:
HY-B0531S
Alternativnummer:
MCE-HY-B0531S-1MG,MCE-HY-B0531S-5MG
Hersteller:
MedchemExpress
Kategorie:
Biochemikalien
Triflusal-d3 is deuterium labeled Triflusal (HY-B0531). Triflusal is an orally bioavailable, blood-brain barrier-permeable dual Cyclooxygenase-1 (COX-1)/cAMP phosphodiesterase inhibitor. Triflusal inhibits platelet aggregation, NF-kappaB activation, iNOS activity, and prostaglandin synthesis in ischaemic tissue. Triflusal stimulates neutrophil nitric oxide production, eNOS protein expression, and cNOS activity. Triflusal alleviates cerebral ischemic injury in rats and ameliorates pathological lesions and related gene expression in transgenic Alzheimers disease models. Triflusal can be used for the research of thromboembolic/ischemic cardiovascular and cerebrovascular diseases, and Alzheimers disease[1].
