Triflusal-d3, CAS [[2748541-63-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-B0531S
Supplier Catalog Number:
HY-B0531S
Alternative Catalog Number:
MCE-HY-B0531S-1MG,MCE-HY-B0531S-5MG
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Triflusal-d3 is deuterium labeled Triflusal (HY-B0531). Triflusal is an orally bioavailable, blood-brain barrier-permeable dual Cyclooxygenase-1 (COX-1)/cAMP phosphodiesterase inhibitor. Triflusal inhibits platelet aggregation, NF-kappaB activation, iNOS activity, and prostaglandin synthesis in ischaemic tissue. Triflusal stimulates neutrophil nitric oxide production, eNOS protein expression, and cNOS activity. Triflusal alleviates cerebral ischemic injury in rats and ameliorates pathological lesions and related gene expression in transgenic Alzheimers disease models. Triflusal can be used for the research of thromboembolic/ischemic cardiovascular and cerebrovascular diseases, and Alzheimers disease[1].
