Hydrastine, CAS [[118-08-1]]

Produktübersicht

• Artikelname: Hydrastine, CAS [[118-08-1]]
• Artikelnummer: MCE-HY-B0927
• Hersteller Artikelnummer: HY-B0927
• Alternativnummer: MCE-HY-B0927-10MMX1ML,MCE-HY-B0927-5MG,MCE-HY-B0927-1MG,MCE-HY-B0927-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien
• Alternative Synonym: (-)-beta-Hydrastine, (1R,9S)-beta-Hydrastine

Produktbeschreibung

Hydrastine ((-)-beta-Hydrastine, (1R,9S)-beta-Hydrastine) is a selective competitive inhibitor of tyrosine hydroxylase (TH), inhibiting dopamine biosynthesis (IC50=20.7 µM, PC12 cells). Hydrastine also inhibits the organic cation transporter OCT1 (IC50=6.6 µM). Hydrastine may cause neuronal toxicity through mitochondrial dysfunction rather than oxidative stress damage, and can aggravate cell apoptosis when combined with L-DOPA. Hydrastine can be used to study Parkinsons disease-related dopaminergic neuronal damage[1][2].

Produkteigenschaften

• Molekulargewicht: 383.39
• Reinheit: 99.57
• CAS Nummer: [118-08-1]
• Formel: C21H21NO6
• Target-Kategorie: Dopamine Receptor,OAT,Tyrosine Hydroxylase

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Natural Products