Trimipramine maleate is a 5-HT receptor antagonist, with blood-brain barrier permeability. Trimipramine maleate has pKi binding values of 6.39, 8.10, 4.66 for 5-HT1C, 5-HT2 and 5-HT1A, respectively. Trimipramine maleate is also a potent and selective inhibitor targeting human noradrenaline (hNAT), serotonin (hSERT) and organic cation transporters (hOCT1, hOCT2) with IC50 values of 4.99 µM, 2.11 µM, 3.72 µM, 8.00 µM, respectively. Trimipramine maleate has vascular activity and anxiolytic efficacy[1][2][3][4].
Molekulargewicht:
410.51
Reinheit:
99.97
CAS Nummer:
[521-78-8]
Formel:
C24H30N2O4
Target-Kategorie:
5-HT Receptor,Bacterial
Anwendungsbeschreibung:
MCE Product type: Reference compound
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