Geniposidic acid, CAS [[27741-01-1]]

Produktübersicht

• Artikelname: Geniposidic acid, CAS [[27741-01-1]]
• Artikelnummer: MCE-HY-N0010
• Hersteller Artikelnummer: HY-N0010
• Alternativnummer: MCE-HY-N0010-10MMX1ML,MCE-HY-N0010-100MG,MCE-HY-N0010-10MG,MCE-HY-N0010-5MG,MCE-HY-N0010-50MG,MCE-HY-N0010-500MG,MCE-HY-N0010-25MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

Geniposidic acid is an orally active FXR modulator and SIRT6 activator. Geniposidic acid binds to the Ser332 and His447 sites on the FXR ligand-binding domain, thereby driving nuclear translocation, coactivator recruitment, and transcription of downstream bile acid and cholesterol metabolism-related genes. Geniposidic acid improves metabolic dysfunction-related fatty liver disease by activating the SIRT6 signaling pathway. Geniposidic acid inhibits inflammation and modulates gut microbiota to alleviate colitis. Geniposidic acid can be used in research on drug-induced liver injury, inflammatory bowel disease, metabolic dysfunction-related fatty liver disease, and metabolic dysfunction-related steatohepatitis[1][2][3].

Produkteigenschaften

• Molekulargewicht: 374.34
• Reinheit: 98.87
• CAS Nummer: [27741-01-1]
• Formel: C16H22O10
• Target-Kategorie: FXR,Interleukin Related,Sirtuin,TNF Receptor

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Natural Products