Geniposidic acid, CAS [[27741-01-1]]

Product Overview

• Article Name: Geniposidic acid, CAS [[27741-01-1]]
• Biozol Catalog Number: MCE-HY-N0010
• Supplier Catalog Number: HY-N0010
• Alternative Catalog Number: MCE-HY-N0010-10MMX1ML,MCE-HY-N0010-100MG,MCE-HY-N0010-10MG,MCE-HY-N0010-5MG,MCE-HY-N0010-50MG,MCE-HY-N0010-500MG,MCE-HY-N0010-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Geniposidic acid is an orally active FXR modulator and SIRT6 activator. Geniposidic acid binds to the Ser332 and His447 sites on the FXR ligand-binding domain, thereby driving nuclear translocation, coactivator recruitment, and transcription of downstream bile acid and cholesterol metabolism-related genes. Geniposidic acid improves metabolic dysfunction-related fatty liver disease by activating the SIRT6 signaling pathway. Geniposidic acid inhibits inflammation and modulates gut microbiota to alleviate colitis. Geniposidic acid can be used in research on drug-induced liver injury, inflammatory bowel disease, metabolic dysfunction-related fatty liver disease, and metabolic dysfunction-related steatohepatitis[1][2][3].

Product Properties

• Molecular Weight: 374.34
• Purity: 98.87
• CAS Number: [27741-01-1]
• Formula: C16H22O10
• Target: FXR,Interleukin Related,Sirtuin,TNF Receptor

Application Notes

• Application Notes: MCE Product type: Natural Products