Mollugin is an orally active and potent NF-kappaB inhibitor. Mollugin induces S-phase arrest of HepG2 cells, and increased intracellular reactive oxygen species (ROS) levels. Mollugin induces DNA damage in HepG2 cells, as well as an increase in the expression of p-H2AX. Mollugin shows anti-cancer effect by inhibiting TNF-alpha-induced NF-kappaB activation. Mollugin enhances the osteogenic action of BMP-2 (bone morphogenetic protein 2) via the p38-Smad signaling pathway[1][2][3].
Molekulargewicht:
284.31
Reinheit:
99.79
CAS Nummer:
[55481-88-4]
Formel:
C17H16O4
Target-Kategorie:
Apoptosis,c-Myc,JAK,NF-kappaB,Reactive Oxygen Species (ROS),VEGFR
Anwendungsbeschreibung:
MCE Product type: Natural Products
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
