Cucurbitacin E is a CDK1 inhibitor that significantly inhibits the activity of the cyclin B1/CDC2 complex. Cucurbitacin E also induces PANoptosis in adrenocortical carcinoma cells in a ZBP1-dependent manner. Cucurbitacin E exhibits synergistic effects with Mitotane (HY-13690), when used in combination, they effectively eliminate tumors[1][2][3].
Molekulargewicht:
556.69
Reinheit:
99.92
CAS Nummer:
[18444-66-1]
Formel:
C32H44O8
Target-Kategorie:
Autophagy,CDK,PANoptosis
Anwendungsbeschreibung:
MCE Product type: Natural Products
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