8-O-Acetylharpagide, CAS [[6926-14-3]]

Produktübersicht

• Artikelname: 8-O-Acetylharpagide, CAS [[6926-14-3]]
• Artikelnummer: MCE-HY-N0757
• Hersteller Artikelnummer: HY-N0757
• Alternativnummer: MCE-HY-N0757-20MG,MCE-HY-N0757-10MMX1ML,MCE-HY-N0757-5MG,MCE-HY-N0757-10MG
• Hersteller: MedchemExpress
• Kategorie: Biochemikalien

Produktbeschreibung

8-O-Acetylharpagide is an iridoid glycoside compound. 8-O-Acetylharpagide exhibits anti-aging activity at low doses and anticancer activity at high doses. 8-O-Acetylharpagide induces late-stage apoptosis and necrosis-like death in cancer cells, and downregulates anti-apoptotic proteins such as Akt, p-Akt and Bcl-2. 8-O-Acetylharpagide is mainly metabolized in rats via demethylation, hydrolysis and glucuronidation, and its active metabolites downregulate the AKT/NF-kappaB/MMP9 signaling axis. 8-O-Acetylharpagide exerts vasoconstrictive effects by activating vascular alpha-adrenoceptor[1][2][3].

Produkteigenschaften

• Molekulargewicht: 406.38
• Reinheit: 99.75
• CAS Nummer: [6926-14-3]
• Formel: C17H26O11
• Target-Kategorie: Adrenergic Receptor,Akt,Apoptosis,Bcl-2 Family

Anwendungsbeschreibung

• Anwendungsbeschreibung: MCE Product type: Natural Products