Swertiamarin is an orally active natural product with hypoglycemic, lipid-lowering, anti-rheumatic, and antioxidant activities. Swertiamarin can regulate the levels of pro-inflammatory cytokines, MMP, and NF-kappaB, and promote osteoblast proliferation. Swertiamarin has antioxidant and hepatoprotective effects against carbon tetrachloride induced rat liver toxicity through the Nrf2/HO-1 pathway. Swertiamarin can attenuate inflammatory mediators by regulating JAK2/STAT3 transcription factors in adjuvant induced arthritis rats. Swertiamarin can be used in the research of diabetes and arthritis[1][2][3][4][5].
Molekulargewicht:
374.34
Reinheit:
99.03
CAS Nummer:
[17388-39-5]
Formel:
C16H22O10
Target-Kategorie:
JAK,Keap1-Nrf2,MMP,NF-kappaB
Anwendungsbeschreibung:
MCE Product type: Natural Products
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