Swertiamarin is an orally active natural product with hypoglycemic, lipid-lowering, anti-rheumatic, and antioxidant activities. Swertiamarin can regulate the levels of pro-inflammatory cytokines, MMP, and NF-kappaB, and promote osteoblast proliferation. Swertiamarin has antioxidant and hepatoprotective effects against carbon tetrachloride induced rat liver toxicity through the Nrf2/HO-1 pathway. Swertiamarin can attenuate inflammatory mediators by regulating JAK2/STAT3 transcription factors in adjuvant induced arthritis rats. Swertiamarin can be used in the research of diabetes and arthritis[1][2][3][4][5].
Molecular Weight:
374.34
Purity:
99.03
CAS Number:
[17388-39-5]
Formula:
C16H22O10
Target:
JAK,Keap1-Nrf2,MMP,NF-kappaB
Application Notes:
MCE Product type: Natural Products
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